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Therapeutic Drug Monitoring     

 

  TDM is defined as the use of drug levels, pharmacokinetic principles and pharmacodynamic factors to optimise drug therapy in individual patients.

1.    Main Objectives :

    1. To optimise drug therapy / improve drug efficacy

    2. To minimize drug toxicity / side effects
    3. To determine patientís compliance on long term therapy
2.    Drugs monitored :
    1. Amikacin
    2. Gentamicin
    3. Netilmicin
    4. Theophylline
    5. Digoxin
    6. Valproic acid
    7. Phenytoin
    8. Phenobarbitone
    9. Carbamazepine
    10. Paracetamol
    11. Salicyclic Acid
    12. Vancomycin
 
At present, the Pharmacist from Bukit Padang Hospital helps out in this unit. Two pharmacy assistant ad 1 student Pharmacy Assistant  assist in this unit. Our service is extended to all government hospitals(19 hospitals) throughout the state of Sabah.


3.    Achievement

 

Year

No. of samples

No. of assays done

1993 863 920
1994 1768 1986
1995 1298 1463
1996 1363 1524
1997 742 874
1998 1266 1396
1999 1416 1521
2000 1449 1660
2001 1864 2175
2002 1661 1800

 

QAP Indicator:

Proportion of assays interpreted & recommendations communicated to the requesting limit / Dr to the total no. of assays received within the same working day. (Standard not less than 75%).  For 2002, our achievement was 93.06%.

 

4.      Plans for 2003

        4.1    No. of assays : min. of 1600
        4.2    To start Cyclosporin monitoring.